Animal Alternative Study - In vitro Eye Irritation (MCTT HCE™)

Outline

This study evaluates chemicals that do not require classification and labeling for eye irritation or eye damage by measuring cytotoxicity using the WST-1 method with a commercially available RhCE model.

Guidelines
  • OECD Guidelines 492(Reconstructed human Cornea-like Epithelium (RhCE) test method for identifying chemicals not requiring classification and labelling for eye irritation or serious eye damage)
  • 국립환경과학원 고시 화학물질의 시험방법에 관한 규정; 제5장 건강영향 시험분야, 제64항 생체 외 눈자극 및 손상시험(인체각막모델시험)