Developmental and Reproductive Toxicology - Combined Repeated Dose Toxicity Study with the Reproduction/Developmental Toxicity Screening Test

Outline

Combined Repeated Dose Toxicity Study with the Reproduction/Developmental Toxicity Screening Test is a test that combines the evaluation of repeated dose toxicity, including the toxicity, target organs, and accumulation potential of the test substance, along with reproductive and developmental toxicity, including effects on gonadal function, mating behavior, pregnancy, fetal development, and parturition, as well as endocrine disruption.

Guidelines
  • OECD Guidelines 422(Combined Repeated Dose Toxicity Study with the Reproduction/Developmental Toxicity Screening Test)
  • 국립환경과학원 고시 화학물질의 시험방법에 관한 규정; 제5장 건강영향 시험분야, 제41항 병합생식/발달독성 선별시험 및 반복투여독성시험